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Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed)
National Institutes of Health
Currently Open
As of Jan 8, 2026
Eligible Applicants
Others (see text field entitled "Additional Information on Eligibility" for clarification)Native American tribal governments (Federally recognized)State governmentsSpecial district governmentsNonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher educationPublic and State controlled institutions of higher educationPublic housing authorities/Indian housing authoritiesPrivate institutions of higher educationSmall businessesCounty governmentsCity or township governmentsNative American tribal organizations (other than Federally recognized tribal governments)Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher educationIndependent school districtsFor profit organizations other than small businesses
Overview
This Notice of Funding Opportunity (NOFO) invites applications that propose to use mouse models to conduct rigorous preclinical testing of drugs or drug combinations currently used for other conditions, as well as investigational drugs at various stages of clinical development, predicted to be efficacious in AD/ADRD. This initiative will also support preclinical testing of repurposable or investigational drug candidates in combination with non-pharmacologic interventions leading to robust translational outcomes. The central goal is to establish robust proof of concept that will enable rational drug repurposing and combination therapy development for the treatment and prevention of AD/ADRD.
Funding Information
Total estimated funding: $1,000,000
Eligibility Requirements
- Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
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Data Source & Verification
Source: www.grants.gov
Last Verified: Jan 8, 2026, 5:28 PM
Important: Always verify current details directly on the official grant website before applying.