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Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required)

National Institutes of Health
Currently Open As of Jan 8, 2026
Application Opens Nov 26, 2024
Deadline Oct 15, 2027
Geography Not specified
Eligible Applicants
Public and State controlled institutions of higher educationCounty governmentsSmall businessesOthers (see text field entitled "Additional Information on Eligibility" for clarification)State governmentsSpecial district governmentsCity or township governmentsNative American tribal governments (Federally recognized)Public housing authorities/Indian housing authoritiesNonprofits having a 501(c)(3) status with the IRS, other than institutions of higher educationFor profit organizations other than small businessesPrivate institutions of higher educationIndependent school districtsNative American tribal organizations (other than Federally recognized tribal governments)Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

Overview

Development of Psychosocial Therapeutic and Preventive Interventions for Mental Disorders (R61/R33 Clinical Trial Required). As part of NIMH's clinical trials pipeline, this NOFO encourages pilot research developing and testing novel psychosocial interventions and/or targets. Consistent with NIMH's emphasis on the experimental therapeutics approach to intervention development, it intends to speed the translation of emergent research in basic, behavioral, cognitive, affect, and neuropsychological science into preventative or therapeutic interventions. This RFA will provide up to two years of support for evaluation of target engagement and establishment of intervention parameters, and up to three years of support to replicate target engagement from prior studies and to test the association between target engagement and change in clinical outcome(s).

Eligibility Requirements

  • Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Contact Information

Contact: National Institutes of Health

Email:

Phone: 301-402-2541

Next Steps

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Data Source & Verification

Source: www.grants.gov
Last Verified: Jan 8, 2026, 5:28 PM
Important: Always verify current details directly on the official grant website before applying.